If you’ve spent any time on social media lately, you might have seen conflicting claims about GLP-1 weight loss medications. One post says they’ll completely kill your appetite. Another warns about scary side effects. Someone else declares losing weight this way is “cheating.”
With all the noise out there, it’s tough to know what’s actually true about these medications. We asked registered dietitians to set the record straight on the biggest myths floating around.
Myth 1: You’ll Never Be Hungry on a GLP-1
Since these medicines hit the mainstream, you’ve probably heard people claim they completely eliminate appetite. Some corners of the internet are full of users saying they have to force themselves to eat.
The Truth: GLP-1s Reduce Appetite (1), Not Eliminate It
While some people do experience a significant drop in appetite, (1) total loss of hunger isn’t the goal. “If someone is finding it hard to eat or their appetite has changed significantly, it’s important to share that information with their healthcare provider so that any concerns can be addressed early and often,” says Melissa Jaeger, dietitian and MyFitnessPal Head of Nutrition. It’s important to focus on consuming enough food and a balanced diet while on GLP-1s to reduce the risk of nutrition deficiencies. (1)
GLP-1s work through multiple mechanisms beyond just curbing hunger. (1) They can also slow gastric emptying, regulate blood sugar, and help reduce “food noise” (that constant mental chatter about food). (1) Weight loss is just one result someone may see while taking a GLP-1. (1).
Myth 2: You’ll Drop a Lot of Weight Fast
Seeing dramatic celebrity transformations on TV may make it easy to believe GLP-1s will melt pounds away practically overnight, without much effort on your part.
The Truth: Weight Loss Looks Different for Everyone
“Whether in your feed or on TV you may see the most dramatic before and after results but they often skip providing the context on what it took and the time it took for the individual to achieve those results. It’s important to remember that gradual weight loss is recommended and completely normal,” (4) says Jaeger. Your starting weight, diet and exercise habits, dosage, and genetics all influence your specific timeline.
A balanced weight loss rate is typically 1-2 pounds per week. (4) Just like any other weight loss approach, slow and steady tends to win the race with GLP-1s. Focus on what’s realistic for your body, not what you see on your screens.
Myth 3: GLP-1s Will Make You Look Bad
You’ve probably heard about “Ozempic face” — a term that refers to a hollowed-out, gaunt appearance supposedly caused by these medications. (5)
The Truth: Dramatic Changes to Appearance Aren’t Inevitable
Here’s the thing: any significant weight loss can result in changes like loose skin or facial fat loss. (6) This isn’t unique to GLP-1s. (6)
“The appearance-focused narrative ignores the health improvements people may experience while taking a GLP-1, like better blood sugar management, (7) weight management, reduced cardiovascular risk and more (1),” says Jaeger.
Myth 4: You Can Use GLP-1s Short-Term to Jump-Start Weight Loss
Maybe you’re thinking: I’ll just take this medication for a few months to get things moving, then stop once I’ve hit my goal weight. It sounds logical, right?
The Truth: GLP-1s Are Designed for Long-Term Use
“It’s understandable that individuals may not want to stay on a medication long-term and in fact research has shown that many discontinue taking a GLP-1 medication within a year and some may go back on the medication but not all, ” (8) says Jaeger. “However, one study has shown that people regain about two-thirds of the weight they lost after stopping the medication. (9) This is why building strong diet and exercise habits is a key component of any weight loss journey.” (1) Before making any changes to your prescription medications it’s imperative that you speak with your healthcare provider.
GLP-1 treatment can be viewed as a long-term commitment for many people. (2)
Myth 5: You Can Eat Whatever You Want and Skip Exercise
Given how effective GLP-1s can be (10), you might assume diet and exercise become optional. After all, if the medication is doing the heavy lifting, why bother with the rest?
The Truth: Nutrition and Movement Still Matter
Weight loss is still about energy balance; your food intake and activity levels always play a role. (1) “GLP-1s may serve as one piece of the weight loss puzzle. Forming healthy habits when it comes to your diet and exercise are critical components of your weight loss journey,” says Jaeger.
Certain nutrients become especially important when you’re losing weight while on a GLP-1. (1) Protein supports muscle mass during periods of weight loss.(11) Meanwhile, resistance exercise supports muscle mass (11) while burning calories (12), plus all the other physical and mental health benefits that come with regular exercise. (13)
Myth 6: Taking GLP-1s Is “Cheating” at Weight Loss
There’s still a lingering belief that “real” weight loss only counts if you do it through diet and exercise alone. Using medication? That’s taking the easy way out, or so the myth goes.
The Truth: Treating Obesity With Medication Isn’t Cheating
Obesity is recognized as a chronic, complex disease in clinical research and by public health organizations.(4) Medication may be used to treat this chronic disease, (3), just like diabetes, (14) hypertension, (15) or any other chronic condition.
“Managing a chronic condition is no easy task, and everyone’s journey to better health looks different,” says Jaeger. “Whether someone is using lifestyle changes, medication or a combination of both, their efforts call for our understanding, not judgement.”
Myth 7: You Need Extremely High Amounts of Protein
Browse any GLP-1 forum and you’ll see people claiming they’re eating 150 plus grams of protein daily, chugging multiple protein shakes, and obsessing over hitting massive protein targets.
The Truth: Moderate Protein Increases Are Usually Enough
Yes, protein is important for preserving muscle and staying full during weight loss. But you don’t need to go overboard. (16) “Most people do well with a moderate increase,” says Stephanie Saletta, dietitian and MyFitnessPal Sr. Lead Nutrition Scientist. “It’s more about consistency and balance than hitting extreme numbers.”
Research suggests aiming for up to 1.2-1.5 grams per kilogram of your ideal body weight, or 80-120g per day for most people. That’s far from the triple-digit targets you might see online. (1)
Myth 8: Everyone Experiences Severe Digestive Side Effects
Horror stories about nausea, vomiting, and other digestive issues dominate online discussions about GLP-1s. It’s enough to make anyone hesitate before starting these medications.
The Truth: Side Effects Vary and Often Improve Over Time
While digestive side effects are common, they’re not universal or permanent for most people. “Many patients experience mild nausea when starting or increasing their dose, but it typically improves within a few weeks as your body adjusts,” says Stephanie Saletta. (17)
Working closely with your healthcare provider to titrate your dose properly can minimize side effects. Eating smaller, more frequent meals and avoiding high-fat foods can also help manage digestive discomfort. (1)
Myth 9: You’ll Lose Only Fat (Not Muscle)
Some people assume that because GLP-1s are so targeted and effective, they’ll only burn fat while preserving all your muscle mass automatically.
The Truth: Muscle Loss Can Happen Without the Right Support
“Any significant calorie deficit puts you at risk of losing more muscle than you’d like along with fat,” says Saletta. “That’s why adequate protein intake and resistance training are so critical while taking GLP-1s.” (1)
The medication doesn’t discriminate between fat and muscle loss. You need to actively work to preserve muscle through nutrition (especially protein) and strength training exercises. (1)
Myth 10: If You’re Not Losing Weight Fast, the Medication Isn’t Working
When your coworker lost 15 pounds in their first month on a GLP-1 but you’ve only lost 4, it’s natural to worry the medication isn’t working for you.
The Truth: Slower Weight Loss Doesn’t Mean Failure
“Response to GLP-1s is highly individual,” says Saletta. “Scientists are still learning about the factors that influence weight loss on GLP-1. Because there’s so much to learn, comparing yourself to others isn’t helpful.” (18)
Even if the scale isn’t moving as quickly as you’d hoped, look at other markers: Are you feeling better? (19) Is your blood sugar improving? (20) Are you experiencing less food noise? (21) These are all signs the medication is working, even if weight loss is gradual.
Myth 11: You Can’t Drink Alcohol on GLP-1s
Some online communities suggest you need to completely eliminate alcohol while taking GLP-1 medications, making it seem like the two are incompatible.
The Truth: Moderation Is Key, But Alcohol Isn’t Forbidden
“Current guidance doesn’t rule out alcohol outright,” says Saletta. “It’s recommended to have minimal alcohol intake, though, because it may worsen certain gastrointestinal symptoms like nausea and acid reflux.” (1)
Many people also find their tolerance for alcohol decreases on GLP-1s, or that they simply don’t crave it as much. (22) (23) If you do choose to drink alcohol, start slowly, stay hydrated, and pay attention to how your body responds. As always, talk to your healthcare provider about what’s appropriate for your situation.
The Bottom Line
GLP-1 medications are powerful tools for managing weight and metabolic health–but they’re not magic pills, and they’re not without nuance. The reality is more complex than what you’ll see in most social media posts or casual conversations.
If you’re considering these medications or currently taking them, your best source of information is always going to be your healthcare team. They can help you separate evidence-based facts from viral fiction.
And remember: using medication to support your health goals isn’t something to feel ashamed about. It’s a legitimate medical intervention that, when combined with sustainable lifestyle habits, can help many people achieve better health outcomes.
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